The best way to take vitamin D is with a meal and it doesn’t matter what time of day. Ideally you are getting your vitamin D from foods and daily multivitamin & mineral formula (MVM), which should always be taken with one of your larger meals. A good MVM contains 600-1000ius of vitamin D. If you need more based on a doctor’s recommendation, you may need to take a separated vitamin D supplement but you would still take it daily and with a meal.